Addressing the idiosyncratic needs of Orthodox Jewish couples requesting sex selection by preimplantation genetic diagnosis (PGD)

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Preimplantation Genetic Diagnosis (PGD)

Preimplantation genetic diagnosis (PGD) is a reproductive technology used with an in vitro fertilization (IVF) cycle to increase the potential for a successful pregnancy and delivery. The most common applications for PGD include testing for extra or missing chromosomes (aneuploidy screening), familial structural chromosome rearrangements, and diagnosis of genetic disease in couples of increased...

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SEX SELECTION Elective Gender Selection, Preimplantation Genetic Diagnosis, Pgd, Sperm Sorting, Ericsson Method

Following ethical issues, many of unwanted pregnancies and abortions can be avoided. Several factors such as cultural, social, religious, and economic issues, as well as medical reasons such as the existence of some diseases related to chromosome X encourage couples to choose traditional or new treatment methods for selecting their child’s gender. The establishment of family balance is another ...

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Preimplantation genetic diagnosis (PGD) for heritable neoplasia.

UNLABELLED Especially applicable for heritable neoplasia, preimplantation genetic diagnosis (PGD) is possible for any Mendelian disorder whose gene has been localized, whether the molecular basis is known or not. METHODS AND RESULTS PGD requires DNA from gametes (oocytes) or embryos before 6 days postconception, when implantation occurs. Approaches include 1) polar body biopsy, 2) blastomere ...

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Sex selection and preimplantation genetic diagnosis.

In 1994, the Ethics Committee of the American Society of Reproductive Medicine concluded, although not unanimously, that whereas preimplantation sex selection is appropriate to avoid the birth of children with genetic disorders, it is not acceptable when used solely for nonmedical reasons. Since 1994, the further development of less burdensome and invasive medical technologies for sex selection...

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Preimplantation Genetic Diagnosis (PGD) for chromosome rearrangements

• Chromosome rearrangements include Robertsonian and reciprocal translocations (the most common form of chromosome abnormality in humans, present in approximately 1 in 500 individuals), periand paracentric inversions, interand intra-chromosomal insertions, deletions, duplications, and complex chromosome rearrangements (CCRs). • In all cases presenting for PGD, the risk of viable abnormality sho...

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ژورنال

عنوان ژورنال: Journal of Assisted Reproduction and Genetics

سال: 2006

ISSN: 1058-0468,1573-7330

DOI: 10.1007/s10815-006-9047-z